If Pro Tools can sync to an external recorder by way of midi (MTC sync), then the two should be able to work together. You would need a midi in and out connection to your computer, as well as a pair of midi cables to lock the two machines together.
You would also need an audio pathway established to get your audio into protools and back out to the VS. This could be via analog or digital, depending on your computer's audio connections.
You will also need to determine how best to monitor the sound from both machines - depending on your gear.....
It will be more or less seamless, once you have all the pieces in place.
Via MTC and the Roland as an slave to Pro Tools, it works perfect with my VS-1680 with SD card Mod and a Netbook running Pro Tools LE 8.
Usually I sync them to record Drums, bass and guitars at the same time, and with VS Wave Export I transfer all the recorded data in the VS and imported to the Pro Tools session.
If your intention is at one stage transfer all the tracks you record on the VS inside the Pro Tools session, if you do the transfer recording each track via analog…. Its not necesary to match the sample rate or the bit resolution….. But,,,, if you do it like I do, transfer them via a Windows software called VS wave Export, here is better to match the bit and sample rate….
In this post I make some time ago you wiil see how I transfer the tracks recorded on the VS via this software….